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Why is pyridostigmine preferred over neostigmine? Neostigmine and pyridostigmine are quaternary amines that are incompletely absorbed from the gut. Pyridostigmine is preferred for the treatment of myasthenia gravis because it has a longer duration of action and is less likely to cause unwanted effects.
How effective is IVIG? Whether IVIG is effective in adults with mild disease or in those who start treatment more than 2 weeks after the onset of symptoms is uncertain. There is no evidence that combining IVIG with preceding plasma exchange is of added benefit.
Can I just stop taking mestinon? It may be helpful to skip a dose to see if there is any effect. Mestinon has no actual effect on the disease process. It really only helps the nerves communicate with the muscles better, so stopping the drug will not have any effect on the disease activity.
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