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Crohn's disease is not an metronidazol approved indication for FLAGYL ER 750 mg tablets . Patients with Crohn's disease metronidazol are known to have an increased incidence of gastrointestinal and certain extraintestinal cancers . A cause and effect relationship metronidazol has not been established . There have been some reports in the medical metronidazol literature of breast and colon cancer in Crohn's disease patients who have been treated with metronidazole at high doses for extended periods of time .
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