Further research need to be done to see if this happens. Signs of Scleroderma usually start with appearance of a blue spot on the epidermis due to blocked capillary RenewElle veins activated by the thickening cells. The colour change is associated often by an itchiness or a sense of pain. In more severe situations of scleroderma bodily places of one's human body program are affected due to the building up of one's human body program. This is called Endemic Sclerosis. It can affect the breathing, kidney program or even the heart.

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